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Questified Chocolate Caramel Pecan Ice Cream Bars

By
Robert Day
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0
Questified Chocolate Caramel Pecan Ice Cream Bars


Cheat on ice cream bars with ice cream bars. Ice cream bars? Extra like an enormous loophole within the legal guidelines of the flavour universe. Questified Chocolate Caramel Pecan Ice Cream Bars are loaded with caramel goodness and crunchy pecans, all dipped in wealthy scrumptious chocolate. One chunk and also you’ll be satisfied – dishonest by no means tasted so righteous.

Take a look at the total recipe under:

Questified Chocolate Caramel Pecan Ice Cream Bars

 

NUTRITIONAL INFO

CHOCOLATE CARAMEL PECAN ICE CREAM BARS

Yields: 16 servings |  Serving Dimension: 1/2 ice cream bar

Energy: 190  | Protein: 3g  | Fats: 17g | Web Carb: 1g

Whole Carb: 16g   | Sugar: <1g

Substances

CHOCOLATE CARAMEL PECAN ICE CREAM BARS

Technique

  1. Put together an 8×8 inch pan with parchment paper.
  2. Let the ice cream sit at room temperature for five minutes.
  3. Scoop the ice cream into the pan and unfold it out in a good layer. Chop the Quest Hero Bar into small items and sprinkle them over the ice cream. Chill in a single day.
  4. Minimize the ice cream into 8 rectangles and insert a popsicle stick into every. Return to the freezer for 1 hour.
  5. Soften the chocolate and coconut oil collectively in a glass cup and dip every popsicle into the chocolate after which lay each a baking sheet lined with parchment paper.
  6. Freeze till able to eat.

6 Cottage Cheese Ice Cream Recipes – Straightforward & Wholesome

By
Robert Day
-
0
6 Cottage Cheese Ice Cream Recipes – Straightforward & Wholesome


Cottage cheese has been a beloved selection for health-conscious people attributable to its dietary worth and repute as an efficient superfood for weight reduction. Just lately, it has gained great reputation on TikTok and different social media platforms, serving as the first ingredient within the newest craze: cottage cheese ice cream recipes.

Uncover the simplicity of making a tasty frozen deal with with cottage cheese that not solely satisfies your cravings but in addition contributes to your well-being. Discover this flourishing social media development and uncover the fascinating insights. Plus, take pleasure in our assortment of wholesome and pleasant cottage cheese ice cream recipes beneath!

Is Cottage Cheese Ice Cream Wholesome?

Cottage cheese6 Cottage Cheese Ice Cream Recipes – Straightforward & Wholesome

Cottage cheese is the primary ingredient in cottage cheese ice cream, making it a more healthy choice than many different frozen desserts. As soon as known as “curds and whey, cottage cheese is a straightforward meals that individuals have been making for generations. In contrast to many different kinds of cheese, cottage cheese is just not aged or hardened. It’s recent and creamy once you eat it.

In response to the California Dairy Press Room and Assets, “Cottage cheese is made by including an acid to pasteurized milk which causes a separation of the milk solids from the whey.” The acid is normally lactic acid from a micro organism tradition or a “food-grade acid” like vinegar.

“After the curd is fashioned, it’s gently minimize into items that enable extra whey to empty from the curds,” explains the California Dairy Press Room and Assets. “The curds are additional cooked and pressed gently to expel extra whey. The curds are rinsed and salt is added.”

Cottage cheese is excessive in protein but decrease in fats and energy, making it an excellent meals for weight reduction. The truth is, full-fat cottage cheese is simply four-percent fats. (As compared, different cheeses are round 30-percent fats.)

A half-cup serving of four-percent cottage cheese has 110 energy and 13 grams of protein. The curds come from casein, a protein that’s particularly helpful for constructing and repairing muscle mass. That’s why so many train lovers are consuming cottage cheese today. For a similar causes, it may be precious for anybody beginning a exercise routine or attempting to eat effectively to shed additional kilos.

Casein is one in every of two sorts of protein in dairy merchandise. (Whey is the opposite.) Casein is absorbed by your physique extra slowly than different kinds of protein. That retains you feeling full and energized lengthy after you eat it.

Cottage cheese can be a wealthy supply of calcium, a mineral that performs a key position in sustaining bone well being and regulating blood stress.

Making Cottage Cheese Ice Cream

Woman using blenderWoman using blender

We tasked our recipe developer with making a number of completely different cottage cheese ice cream recipes that match into your Nutrisystem weight reduction plan. After experimenting and style testing recipes made with several types of cottage cheese, it was discovered that common four-percent cottage cheese was the winner. Varieties with much less fats than this include an excessive amount of water and the top consequence didn’t style as much as par.

There isn’t a dietary distinction between massive and small curd cottage cheese, however some individuals discover the massive curd tastes barely much less acidic. Both works for making ice cream.

Making the ice cream is really easy. No ice cream churn or every other particular gear is required. Together with the cottage cheese, all you want is a pure sweetener comparable to honey or maple syrup. You too can add in different tasty elements that you just take pleasure in (extra on that beneath!)

Merely put the ingredient in a blender or meals processor, then whip till every part is clean and creamy. It is going to be a considerably thick liquid with no clumps remaining.

Pour the liquid right into a freezer-safe plastic container and canopy it tightly with a lid. Pop the container into the freezer for 90 minutes to some hours, relying on the recipe. While you’re able to take pleasure in, chances are you’ll must let it sit out at room temperature for 10 to twenty minutes earlier than scooping if it’s utterly frozen. 

Cottage Cheese Ice Cream Concepts and Toppings

Berries frozen dessertBerries frozen dessert

Made with love, home made cottage cheese ice cream presents a refreshing style and a texture that resembles frozen yogurt. Customise your individual distinctive flavors and take pleasure in a customized ice cream expertise. Try these inventive concepts to reinforce your home made delight.

1. Taste Extracts and Spices

You may pump up the style of your home made ice cream with out loading on additional energy. You want just a few drops of taste extracts, comparable to vanilla, peppermint, coconut or lemon. There are such a lot of completely different flavors, so select your favorites and experiment!

Spices comparable to cinnamon, nutmeg, clove and floor ginger additionally give your ice cream a punch of taste. These are all Free meals on the Nutrisystem weight reduction plan, so you should use as a lot of them as you want.

2. Cocoa, Peanut Butter and Espresso Powders

You may embody flavorful powders in your mix to intensify the style of your ice cream. Unsweetened cocoa powder provides your ice cream a chocolaty taste with out including sugar. Peanut butter powder works effectively as a result of it has the flavour of your favourite creamy peanut butter, however far fewer energy as a result of the fat have been eliminated. In case you like coffee-flavored ice cream, add espresso powder.

3. Contemporary and Frozen Fruit

Strawberries, blueberries or raspberries convey shade, diet and pure sweetness to your dessert. Chopped cherries, diced peaches, mango chunks and pineapple items will be integrated into the ice cream or used as a topping for the essential recipe. Mixing a banana into the bottom will make it much more creamy and candy.

4. Different Ice Cream Toppings

If you wish to flip your cottage cheese ice cream right into a sundae, you should use one or two of your each day Extras. Simply remember to persist with the serving sizes within the Nutrisystem Grocery Information, comparable to a half-tablespoon of semi-sweet chocolate chips, two teaspoons of chocolate syrup, or two tablespoons of sunshine whipped topping. With or with out these extras, your cottage cheese ice cream will fulfill your cravings for a cool and candy deal with whereas fueling you up with highly effective protein.

6 Cottage Cheese Ice Cream Recipes

Strive the Nutrisystem taste-tested and accredited cottage cheese ice cream recipes beneath to get began!

strawberry peach cottage cheese ice creamstrawberry peach cottage cheese ice cream

Bask in our delectable Strawberry Peach Cottage Cheese Ice Cream recipe! Expertise the right mix of juicy peaches, ripe strawberries, and creamy cottage cheese for an unforgettable style sensation. Your style buds will crave extra!

Get the Strawberry Peach Cottage Cheese Ice Cream recipe.

churro cottage cheese ice creamchurro cottage cheese ice cream

Strive our delicious and nutritious Churro Cottage Cheese Ice Cream recipe! A velvety mix of cottage cheese, honey and vanilla extract, topped with a pleasant cinnamon contact and graham cracker crunch. This trending dessert is the right steadiness of style and nourishment.

Get the Churro Cottage Cheese Ice Cream recipe.

chocolate peanut butter cottage cheese ice creamchocolate peanut butter cottage cheese ice cream

Crafted with cottage cheese as the bottom and the irresistible mix of chocolate and peanut butter, this creamy and protein-packed ice cream various presents a guilt-free choice for these in search of a candy and satisfying delight. Fulfill your cravings with this heavenly dessert that mixes the goodness of cottage cheese, chocolate and peanut butter!

Get the Chocolate Peanut Butter Cottage Cheese Ice Cream recipe.

Cherry Cheesecake Cottage Cheese Ice CreamCherry Cheesecake Cottage Cheese Ice Cream

Get pleasure from a pleasant concord of a Cherry Cheesecake Cottage Cheese Ice Cream. This distinctive fusion of creamy cheesecake and refreshing ice cream creates a really irresistible deal with. Our recipe combines key elements like cottage cheese, honey, cream cheese, and frozen cherries, setting it other than conventional ice cream recipes. Expertise the luxurious creaminess and candy sensation in each blissful scoop.

Get the Cherry Cheesecake Cottage Cheese Ice Cream recipe.

Chocolate Cottage Cheese Ice Cream with PistachiosChocolate Cottage Cheese Ice Cream with Pistachios

Chocolate Pistachio Cottage Cheese Ice Cream is an beautiful dessert that can revolutionize your desserts. This distinctive recipe completely blends the decadent style of cacao powder with the creamy goodness of cottage cheese, enhanced by the pure sweetness of honey and the satisfying crunch of pistachios. Elevate your dessert sport with this irresistible deal with!

Get the Chocolate Pistachio Cottage Cheese Ice Cream recipe.

cookies and cream cottage cheese ice creamcookies and cream cottage cheese ice cream

Expertise the right fusion of creamy cottage cheese and the traditional cookies and cream combo. This wealthy, velvety deal with is just irresistible. When you strive our beautiful Cookies and Cream Cottage Cheese Ice Cream dessert, there’s no turning again. Deal with your self to the most effective ice cream round!

Get the Cookies and Cream Cottage Cheese Ice Cream recipe.



Friday and Saturday – BionicOldGuy

By
Robert Day
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0
Friday and Saturday – BionicOldGuy


Friday I did a bit of over 2 1/2 hours on my recumbent out Coyote Creek path to Blossom Hill street and again, at a brisk tempo tempo. I seen I used to be getting cranky as a result of my coronary heart price wasn’t fairly as much as what it was speculated to be. So I put my monitor in my pocket and loved the remainder of the journey extra. Tech is nice so long as it doesn’t distract you from having fun with the exercise whereas it’s occurring. I believe I’ll strive retaining it in my pocket sooner or later. I can get as nerdy as I need with the information later after the journey is over.

On Saturday I did a bit of over an hour on native dust with my upright. It was enjoyable utilizing increased electric-assist on the roads to zoom quicker, then utilizing much less help whereas standing or on dust.

Friday’s journey is posted on Strava right here, Saturday right here.

On Friday’s journey I noticed that our Natural grass trimmers are again

Printed by BionicOldGuy

I’m a Mechanical Engineer born in 1953, Ph. D, Stanford, 1980. I’ve been lively within the mechanical CAE discipline for many years. I even have a lifelong curiosity in outside actions and health. I’ve had each hips changed and a coronary heart valve alternative as a result of a genetic situation. This weblog chronicles my adventures in staying lively regardless of these bumps within the street.

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Blended In a single day Oats (4 Methods!)

By
Robert Day
-
0
Blended In a single day Oats (4 Methods!)


Breakfast is served with these scrumptious and nutritious blended in a single day oats! Blended in a single day oats take your favourite solution to eat oats and blends all of it collectively to a brilliant creamy texture. Add your favourite add-ins to make breakfast style like dessert.

On this submit, we’ll train you the best way to make blended in a single day oats plus share 4 scrumptious taste combos the entire household will love.

Four jars of blended overnight oats with different toppings are labeled: strawberry, fudgey, peanut butter, and coconut. Text at the top reads "Blended Overnight Oats.

If you recognize us, you recognize we’ve had a love affair with in a single day oats for almost a decade. It’s such a tremendous breakfast that may be meal prepped for the week and eaten anyplace. Plus, they’re filled with entire grains and are a tremendous supply of protein.

So in the event you’re an in a single day oats lover like us, you’re going to freaking lose it over these blended in a single day oats. We’re sharing one superb blended oats base recipe (that’s delish by itself!) with 4 blended in a single day oats recipes you’re completely going to like, together with:

  • Peanut butter (a basic!)
  • Strawberry
  • Coconut
  • Fudgey

What are blended in a single day oats?

Blended in a single day oats take basic in a single day oats substances like rolled or fast oats, chia seeds, Greek yogurt and almond milk and blends all of it to a brilliant creamy texture in a meals processor. Retailer them within the fridge such as you would conventional in a single day oats, and revel in for breakfast or a protein-packed snack.

What do blended in a single day oats style like?

They style similar to conventional in a single day oats however boast a brilliant creamy and clean texture as a result of the oats have been blended right into a nice grind in a meals processor.

why you’ll love these blended oats

  • One base recipe + 4 superb taste combos
  • Single-serve breakfast or candy snack filled with entire grains
  • Tremendous creamy and clean texture
A blender containing chia seeds, oats, a white creamy substance, and liquid viewed from above on a light-colored surface.
A blender filled with a frothy mixture is shown from above on a light-colored surface. A striped cloth and some spilled oats are visible next to it.A blender filled with a frothy mixture is shown from above on a light-colored surface. A striped cloth and some spilled oats are visible next to it.

Elements for Blended In a single day Oats

The substances for the bottom of those blended in a single day oats recipes are staple substances that you simply in all probability have already got readily available (we’re not simply saying that 😂).

Then, add within the substances for every of the flavour combos to make peanut butter, strawberry, fudgey, or coconut in a single day oats — or heck, whip up a batch of all 4 directly!

right here’s a tip!

Ensure you have ALL the flavour mixture substances and never simply the bottom substances earlier than you begin making these blended in a single day oats recipe in the event you’re planning to make all the flavour combos!

For the bottom

This tremendous easy base recipe for blended in a single day oats tastes nice by itself, or mixed it with any of our 4 taste combos beneath for a burst of taste. You want:

  • Oats: We’ve examined this recipe with each rolled oats and quick-cooking oats and so they each work nice. 
  • Chia seeds: Chia seeds are our secret weapon for thick blended in a single day oats. As chia seeds sit in liquid, they increase and turn out to be gelatinous. DO NOT skip the chia!
  • Maple syrup: That is our most popular all-natural sweetener, however you too can use honey, agave and even brown sugar.
  • Almond milk: Be at liberty to make use of any form of milk with this recipe. We want unsweetened almond milk, however cow, soy, oat, and so forth. work, too!
  • Greek yogurt: Not solely does Greek yogurt add protein, however it should make your oats tremendous creamy. Be at liberty to make use of a plant-based yogurt in the event you’re trying to hold issues vegan.
A bowl of creamy oatmeal topped with peanut butter and chopped nuts. A gold spoon is partially submerged in the oatmeal. Other bowls of similarly prepared oatmeal surround it.A bowl of creamy oatmeal topped with peanut butter and chopped nuts. A gold spoon is partially submerged in the oatmeal. Other bowls of similarly prepared oatmeal surround it.

For the Peanut Butter

All it is advisable to add to the bottom recipe is creamy peanut butter, and similar to that you simply’ve acquired the right peanut butter blended in a single day oats able to get pleasure from:

  • All pure, creamy peanut butter
A glass bowl of chocolate oatmeal topped with raspberries, chocolate chips, and a dusting of cocoa powder. A spoon rests inside the bowl. Other oatmeal bowls are partially visible around it.A glass bowl of chocolate oatmeal topped with raspberries, chocolate chips, and a dusting of cocoa powder. A spoon rests inside the bowl. Other oatmeal bowls are partially visible around it.

For the Fudgey

Fudgey and tremendous chocolate-y, this taste mixture is principally dessert for breakfast:

  • Cocoa powder 
  • Chocolate chips 
  • Almond milk
  • Maple syrup
A bowl of oatmeal topped with sliced strawberries, granola, and a gold spoon placed in it.A bowl of oatmeal topped with sliced strawberries, granola, and a gold spoon placed in it.

For the Strawberry

Sliced strawberries and maple syrup mix collectively for a delish mixture that truthfully rivals strawberry cheesecake:

A glass bowl filled with a creamy mixture topped with toasted coconut flakes and chia seeds, with a gold spoon inserted into it. Other similar bowls are partially visible around it.A glass bowl filled with a creamy mixture topped with toasted coconut flakes and chia seeds, with a gold spoon inserted into it. Other similar bowls are partially visible around it.

for the Coconut

This coconut taste mixture tastes like coconut cream pie for breakfast 😀

  • Exchange almond milk with coconut milk 
  • Vanilla extract
  • Unsweetened shredded coconut 
  • Maple syrup

The way to Make Blended In a single day Oats

Making these blended in a single day oats is as straightforward as 1-2-3:

  1. Place the entire substances for the bottom of the oats right into a high-speed blender or meals processor.
  2. Select a taste and add these substances in with the bottom substances. 
  3. Mix till clean. Eat instantly or refrigerate for later 🤩

blender on clear background.blender on clear background.

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Storage

One of the best ways to retailer blended in a single day oats is in a glass container within the fridge. You may both retailer one batch in a big meal-prep container, or you possibly can retailer them individually (our favourite jars are these W&P jars) for a straightforward grab-and-go breakfast possibility.

How lengthy do blended in a single day oats final?

Blended in a single day oats will final round 3-5 days within the fridge. In the event you’re utilizing fruit, we advocate days and in the event you’re not utilizing fruit, they’ll final 5 days.

White jars stacked.White jars stacked.

Overhead view of seven jars filled with different varieties of overnight oats topped with ingredients like strawberries, chocolate chips, chia seeds, coconut flakes, and granola, arranged in a pattern.Overhead view of seven jars filled with different varieties of overnight oats topped with ingredients like strawberries, chocolate chips, chia seeds, coconut flakes, and granola, arranged in a pattern.
Top-down view of four jars filled with different flavors of overnight oats, garnished with toppings like strawberries, chocolate, raspberries, nuts, and coconut flakes, arranged in a 2x2 grid.

Blended In a single day Oats Recipe – 4 Methods

These blended in a single day oats take conventional in a single day oats to the subsequent stage by mixing them to a brilliant clean and creamy consistency. We’re sharing 4 of our favourite taste combos!

Prep:20 minutes

Whole:20 minutes

Fats 6

Carbs 38

Protein 10

Elements

Base

Peanut Butter Blended In a single day Oats

  • 2 tablespoons all-natural peanut butter + extra for topping

Fudgey Blended In a single day Oats

Strawberry Blended In a single day Oats

Coconut Cream Pie Blended In a single day Oats

Ideas & Notes

  • Vitamin data is for the bottom substances solely.
  • If you’re making the coconut cream pie oats, substitute the almond milk with coconut milk in step #1).

Vitamin details

Energy: 247kcal Carbohydrates: 38g Protein: 10g Fats: 6g Fiber: 7g Sugar: 7g

Strawberry Basil Feta Bake

By
Robert Day
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0
Strawberry Basil Feta Bake


Strawberry Basil Feta BakeStrawberry Basil Feta Bake

You will love this recipe from the primary aromas – after simply 10 minutes within the oven! Should you’ve heard of the favored TikTok feta and tomato pasta bake we’ve remodeled this meals pattern into a straightforward spring-to-summer pasta. Introducing our Strawberry Basil Feta Pasta. I’m not drooling, you’re drooling!

This can be a low-maintenance recipe with beneath 20 minutes of prep time. And a terrific one to win anybody over at a pot-luck, yard BBQ, or just a household dinner. It’s extraordinarily versatile as you possibly can select your favourite pasta noodles; calling all bow-tie, penne, and rigatoni lovers! This pasta may also be served as a scorching pasta or a chilly pasta salad, as these flavors collectively are simply winners. I really favor it as a chilly pasta salad, however that’s simply me! The sunshine and recent flavors that the strawberries and basil create are too scrumptious.

BTW, I ought to introduce myself… My identify is Kennedy Profaizer and I’m at the moment engaged on my Masters in Dietetics to grow to be a Registered Dietitian. I get pleasure from cooking, sustainability, and the social media side of meals and diet; so working with Serena and Deanna was absolutely the good match!

At first, I used to be very nervous making this. I figured, nicely, that is going to be implausible or an entire dud. I’m glad it was not a dud. The candy juices from the strawberries, blended with the salty creaminess from the feta and the freshness the basil brings in: ugh I’m obsessed!

Query: Should you might be one pasta what would you be? I believe I’d be bow-tie, as a result of I prefer to assume I’m very fancy! 😉

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Description

Like the favored TikTok baked tomato feta recipe, however with new spring and summer season flavors of strawberries and basil. Serve it with pasta as a chilly picnic salad, or room temperature.

  • 2 kilos of recent strawberries, stemmed and quartered
  • 1 block (8 oz) of feta cheese
  • 4 tablespoons of additional virgin olive oil, divided
  • ¼ teaspoon of black pepper
  • 1 pound of your favourite pasta noodles
  • 1 1/2 teaspoon of kosher salt
  • 1 cup of recent basil, chopped
  • 2 tablespoons of decreased balsamic French dressing, non-obligatory

  1.  Preheat oven to 400 levels Fahrenheit. Mist a 9 x 13 inch baking dish with cooking spray.
  2. Add reduce strawberries into baking dish and drizzle strawberries with 2 tablespoons of olive oil; toss with fingers to fully cowl strawberries.
  3. Add block of feta to the center of the dish, no strawberries must be beneath the feta however all strawberries ought to encompass the feta. Drizzle the final 2 tablespoons of olive oil on prime of feta block and sprinkle with pepper. Bake for 40 minutes till feta is a lightweight golden brown and strawberries are mushy and effervescent of their juices.
  4. Whereas the feta and strawberries are cooking, boil water for pasta in a big pot. When boiling, stir within the salt.
  5.  Cook dinner pasta noodles based on bundle instructions. 
  6. Drain pasta noodles when finished cooking al dente; saving ¼ to ½ cup of pasta water earlier than draining. The starch from the pasta water helps thicken pasta sauce. 
  7. As soon as strawberries are finished, break up feta and blend with strawberries. Add blended strawberries and feta sauce to pot of noodles and stir collectively. Add a number of tablespoons of pasta water. End with chopped basil and provides it one other couple stirs.
  8. Serve both heat from the pot into bowls or cool for 2-3 hours within the fridge to function a chilly pasta salad and add non-obligatory drizzle of decreased balsamic French dressing. 

GSK’s Quest to Deliver Myeloma Drug Again to the Market Stops for a Knowledge Drop at ASCO

By
Robert Day
-
0
GSK’s Quest to Deliver Myeloma Drug Again to the Market Stops for a Knowledge Drop at ASCO


A GSK a number of myeloma drug that was withdrawn from the market is accumulating new medical knowledge that might help its return — maybe as an earlier line of remedy. With the most recent outcomes, clinicians and GSK executives say they could have found out how you can handle a lingering query about how you can safely dose the drug, Blenrep.

The new knowledge have been introduced Sunday throughout the annual assembly of the American Society of Medical Oncology in Chicago.

Blenrep is an antibody drug conjugate (ADC) that targets the BCMA protein on a number of myeloma cells, delivering to them a payload of poisonous chemotherapy. There are numerous a number of myeloma medication accessible, however frequent relapse in the sort of blood most cancers means there’s all the time want for brand spanking new therapies.

The brand new Blenrep knowledge are from a Section 3 examine referred to as DREAMM-8, which enrolled 308 sufferers whose a number of myeloma relapsed or had not responded after not less than one earlier line of remedy. The examine in contrast the addition of Blenrep to the accredited Bristol Myers Squibb a number of myeloma drug Pomalyst and the steroid dexamethasone. That remedy mixture was in comparison with the mix of Pomalyst, dexamethasone, and the accredited Takeda Pharmaceutical a number of myeloma drug Velcade. The principle objective is measuring progression-free survival.

The trial outcomes present Blenrep helps sufferers with a number of myeloma reside longer. Within the group who obtained the GSK drug mixture, median progression-free survival has but to be reached on the median mark of 21.8 months. Within the comparator group, the median progression-free survival was 12.7 months. The outcomes for the Blenrep arm translate to a discount within the threat of illness development or demise of 48%, stated Dr. Suzanne Trudel of the Princess Margaret Most cancers Heart, College Well being Community, Toronto, talking throughout a media briefing with journalists.

One of many security dangers related to Blenrep and another ADCs is eye toxicity that results in misplaced or blurry imaginative and prescient. Trudel stated that protocols have been developed over time to raised handle the ocular toxicities with dose holds and changes, enabling sufferers to remain on remedy. She added that ADCs utilized in continual myeloid leukemia confirmed clinicians that it’s obligatory to determine how you can modify dosing to cut back poisonous results.

“All of the ocular occasions are reversible with applicable with dose modifications, dose holds, and dose reductions,” Trudel stated. “This has been the historical past in myeloma as a result of nearly each drug — carfilzomib, selinexor, the bispecifics — in the long run, we’ve needed to learn to use them and dose alter and modify for tolerability.”

Advances in a number of myeloma have come from utilizing a number of medication as frontline remedy, stated Dr. Oreofe Odejide of the Dana Farber Most cancers Institute and the ASCO knowledgeable requested to touch upon the Blenrep outcomes. Consequently, some early-line remedies can embody combos of three and even 4 medication.

“Whereas that has actually improved outcomes for sufferers with myeloma, it additionally signifies that when sufferers relapse, they’ve usually been uncovered, (and) could not reply as properly to many anti-myeloma remedies,” Odejide stated. “So there may be an unmet want for novel mixture therapies within the relapse setting. And [Blenrep], based mostly on this discovering, is absolutely assembly that want squarely.”

Blenrep received accelerated FDA approval in 2020 as a fifth-line a number of myeloma remedy, making it the first-approved BCMA-targeting remedy. In 2022, GSK reported that Blenrep failed to satisfy the progression-free survival most important objective of its confirmatory Section 3 check. In response to an FDA request, GSK withdrew Blenrep from the market. If GSK is ready to return Blenrep to the market, it could discover itself alongside new BCMA-targeting merchandise that embody a cell remedy from BMS and a Johnson & Johnson drug lineup within the illness that features a cell remedy and a bispecific antibody.

GSK has been rebuilding its case for Blenrep with extra medical knowledge. Final 12 months, the drugmaker reported Section 3 knowledge displaying Blenrep beat J&J’s Darzalex in a head-to-head check of the therapies as first-line remedies. Earlier this 12 months, GSK reported a Blenrep drug mixture beat a Velcade drug mixture with outcomes displaying a 59% discount within the threat demise or illness development.

In a separate briefing with journalists, Hesham Abdullah, GSK’s high oncology government, provided an extra attainable clarification for Blenrep’s higher medical trial outcomes. Not solely is the remedy an ADC that delivers a focused cytotoxic drug payload to a number of myeloma cells, it additionally elicits an immune response that helps with the remedy impact, he stated.

The medical trial that supported Blenrep’s accelerated approval examined the drug as a monotherapy in closely pre-treated sufferers. Abullah famous that the most recent exams of the drug are evaluating the drug as a part of remedy combos for sufferers who haven’t been uncovered to many prior strains of remedy. The result’s a length of response and a depth of response that’s translating to enchancment in affected person survival. In GSK’s announcement of Blenrep’s new medical trial outcomes, the corporate stated it continues to share the information and focus on with regulators the trail ahead for the drug.

Photograph by GSK

Cisco Protection Orchestrator’s Path to FedRAMP Authorization

By
Robert Day
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0
Cisco Protection Orchestrator’s Path to FedRAMP Authorization


As an business chief in safety and constructing trusted methods, Cisco continues to make progress on our dedication to ship SaaS options to the federal government. In the present day I’d prefer to shed some mild on the standing and processes concerned for one in all these options because it strikes ahead on reaching FedRAMP® Authorization—Cisco Protection Orchestrator (CDO).

Cisco Protection Orchestrator is a cloud-based multi-device supervisor that allows constant coverage implementation throughout extremely distributed environments. CDO’s centralized administration permits speedy deployment of coverage adjustments when minutes matter, and reusing coverage objects throughout all firewall kind elements reduces each administrative effort and organizational threat. Safety groups that undertake CDO spend much less time deploying and sustaining their firewalls and extra time optimizing insurance policies and managing threats.

Shifting ahead on FedRAMP

Cisco has made nice progress in shifting a wide range of our options by means of the FedRAMP course of. Created to encourage use of cloud computing, FedRAMP serves to streamline the alternate of knowledge and speed up companies inside federal companies, plus enhance their interplay with the general public. In 2023, the FedRAMP Authorization Act was handed, codifying the FedRAMP program because the authoritative standardized method to safety evaluation and authorization for cloud merchandise and choices.

With FedRAMP, federal companies are offered a uniform framework for evaluating, approving, and regularly overseeing cloud companies. This consists of procedures for safety assessments, authorizations, and ongoing surveillance of cloud companies utilized by federal entities. As well as, you need to perceive the next:

  • The US Basic Companies Administration (GSA) administers FedRAMP in collaboration with the Division of Homeland Safety (DHS) and the Division of Protection (DoD).
  • The compliance parameters set by FedRAMP are in alignment with the Nationwide Institute of Requirements and Know-how (NIST) Particular Publication 800-53, which outlines technical requirements for cloud computing.
  • FedRAMP additionally promotes adherence to the Federal Info Safety Administration Act (FISMA) and the OMB Round A-130 by federal companies.

The FedRAMP course of and Cisco Protection Orchestrator

FedRAMP Authorization could be pursued with a person company sponsor or multi-agency authorization. For CDO, Cisco is working with the USA Nationwide Institute of Well being (NIH) as the person company sponsor.

Preparation Section

The preliminary section with particular person company sponsorship is called the Preparation Section. It consists of two key steps if no sponsor company is offered: conducting a Readiness Evaluation and interesting in Pre-Authorization actions.

Preparation Step 1: Readiness Evaluation

The Readiness Evaluation is an non-obligatory stage aimed toward serving to cloud choices receive a sponsor. Readiness assessments are carried out by licensed Third-Get together Evaluation Organizations (3PAOs), who produce a Readiness Evaluation Report (RAR) that exhibits potential sponsoring companies that the answer is able to meet the federal authorities’s safety requirements.

Preparation Step 2: Pre-Authorization

If sponsoring company is offered, you possibly can go straight to Pre-Authorization, skipping the Readiness Evaluation stage. Cisco has accomplished Pre-Authorization with NIH. This implies the CDO crew has applied the requisite technical and procedural necessities and compiled the safety documentation obligatory for the authorization course of.

Throughout this section, Cisco completed the next duties:

  • Demonstrated that the CDO for presidency answer is absolutely constructed and purposeful.
  • Accomplished a CSP Info Kind.
  • Decided the safety categorization of the info that shall be positioned inside the system using the FIPS 199 categorization template together with the suitable steerage of FIPS 199 and NIST Particular Publication 800-60 Quantity 2 Revision 1 to accurately categorize the CDO system based mostly on the varieties of info processed, saved, and transmitted.

After the profitable completion of a kickoff assembly with NIH on February 22, 2024, CDO achieved the In Course of standing on the FedRAMP Market.

Authorization Section

The subsequent step is the Authorization Section, which has two components: Full Safety Evaluation and Company Authorization Course of.

 

Authorization Step 1: Full Safety Evaluation

The primary authorization step is a full safety evaluation by a licensed 3PAO. Earlier than this evaluation, Cisco accomplished the Web site Safety Plan (SSP) and reviewed it with NIH. Schellman Compliance, LLC is the 3PAO answerable for the Safety Evaluation Plan (SAP) for CDO and the Safety Evaluation Report (SAR) that can doc take a look at findings and ideas related to attaining FedRAMP Authorization.

As soon as the 3PAO evaluation is completed, Cisco develops a Plan of Motion and Milestones (POA&M) outlining the plan to handle the take a look at findings within the SAR.

Authorization Step 2: Company Authorization Course of

The second authorization step is Company Authorization, through which NIH will overview the whole authorization bundle and will maintain a SAR debrief with the FedRAMP Venture Administration Workplace. NIH will even implement, take a look at, and doc the customer-responsible controls throughout this section. Then the NIH will carry out a threat evaluation and situation an Approval to Function (ATO) when recognized dangers are sufficiently addressed.

At this level, CDO may have company authorization to function however nonetheless require overview by the FedRAMP PMO to be included within the FedRAMP Market. When completed, the FedRAMP PMO will replace the Market itemizing to replicate FedRAMP Approved Standing and the date of Authorization. The safety bundle will then be made obtainable to company info safety personnel, who can situation subsequent ATOs, by finishing the FedRAMP Bundle Entry Request Kind.

Put up-Authorization

As soon as CDO receives Authorization standing within the FedRAMP Market, it should enter a steady monitoring section to make sure ongoing safety of the system and authorities knowledge. On this section, Cisco submits common safety documentation—together with vulnerability scans, refreshed Plans of Motion and Milestones (POA&M), yearly safety evaluations, stories on incidents, and requests for important adjustments—to every of their company purchasers. Cisco will make use of the FedRAMP safe repository to add steady monitoring content material for all companies that deploy CDO to overview.

Leveraging the Cisco Federal Ops Stack

Cisco is leveraging the Cisco Federal Operational Safety Stack (Fed Ops Stack) as a core element of the CDO FedRAMP course of to hurry future FedRAMP growth and assessments. The Cisco Fed Ops Stack is a centralized set of instruments and companies that cowl roughly 50% of FedRAMP Reasonable necessities. As soon as Fed Ops Stack has obtained authorization to function, together with CDO, Cisco can leverage these shared companies in future SaaS merchandise to make audits and steady monitoring less complicated for Cisco and federal companies.

Pushing ahead on CDO FedRAMP compliance

Our crew at Cisco is absolutely dedicated to getting CDO FedRAMP compliant, so federal companies can simplify their administration of distributed safety insurance policies. We’re happy to have accomplished the Company Evaluate with our company sponsor NIH and achieved In Course of standing. Look ahead to extra updates as we get nearer to full FedRAMP Authorization for CDO, the Cisco Fed Ops Stack, and extra SaaS gives from Cisco.

For extra particulars on the FedRAMP course of, I encourage you to learn Will Ash’s weblog on mapping the FedRAMP journey for Cisco Umbrella for Authorities.

Study extra about Cisco Protection Orchestrator and FedRAMP

 

 

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Our first EVER diet problem!

By
Robert Day
-
0
Our first EVER diet problem!


Are you able to take your intestine well being to the subsequent degree? We’re so excited to announce our model new “Really feel Good Intestine Information” that takes a deep dive into your intestine well being. Study why it issues, find out how to repair it and get a 14-day meal plan that will help you detox, de-bloat and heal your intestine.

And one of the best half? We’re kicking off the brand new information with a Diet Problem, so you may be a part of us in following the information and reworking your intestine well being collectively!

What’s the Really feel Good Intestine Information?

The Really feel Good Intestine Information is our model new information that’s designed that will help you optimize your intestine well being. Contained in the information, you’ll discover a ton of data on find out how to banish bloat and heal your intestine, together with the way it works, why it is necessary, and find out how to preserve it in prime form. We’ve got additionally included a 14-day meal plan that’s particularly designed to help a wholesome intestine. With 24+ scrumptious and nutritious recipes, you may by no means really feel disadvantaged!

Why Be a part of the Problem?

You’ll FINALLY discover ways to de-bloat and heal your intestine! By becoming a member of our Really feel Good 14 problem, you’ll discover ways to debloat and heal you intestine for good! We’re so excited to do that collectively!! You’ll join with different LSF babes who’re doing the problem collectively, share suggestions, and encourage one another. 

Take part

Here is what it’s essential to do:

  1. Get your copy of the Really feel Good Intestine Information!
  2. Learn by the information & familiarize your self with the data + meal plan.
  3. Begin following the meal plan on February nineteenth!
  4. Join with Teamlsf!
  5. Publish in your Instagram story every day for an opportunity to win the giveaway!

Giveaway

We will probably be posting a Printable Calendar/Bingo graphic on @Teamlsf that will probably be your key to win!

Be sure that to maintain this graphic as you have to to submit it & tag us with all 14 days checked off. You’ll then be entered to win 1 of 5 Amazon Contemporary reward playing cards!

We additionally advocate posting the “I’M IN” Graphic firstly of the problem & tag @Teamlsf & @lovesweatfitness!

Why Intestine Well being Issues

Your intestine well being performs an important function in your general well-being. A wholesome intestine is crucial for correct digestion, nutrient absorption, and a powerful immune system. It may possibly additionally affect your temper, power ranges, and even your pores and skin. By prioritizing your intestine well being, you may expertise improved digestion, elevated power, higher psychological readability, and a stronger immune system.

So, are you able to be a part of our first ever diet problem and rework your intestine well being? Get your copy of the Really feel Good Intestine Information immediately and let’s go on this journey collectively. Your intestine will thanks!



Strawberry Salad – A Couple Cooks

By
Robert Day
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0
Strawberry Salad – A Couple Cooks


*In case you have time, toasting the nuts is an effective way to step up the flavors! Add the nuts to a dry skillet and toast for 3 to five minutes over medium warmth, stirring incessantly. Instantly take away to a plate. See The way to Toast Pecans, The way to Toast Almonds, or The way to Toast Walnuts. Different variations on the nuts embrace hazelnuts, chopped pistachios, candied pecans, or candied walnuts.

**Cheese is non-obligatory however provides a welcome savory distinction. We like feta cheese or goat cheese crumbles. Gorgonzola or Parmesan cheese additionally work. Omit cheese for a vegan salad and use maple syrup within the dressing. 

***Contemplate including protein to make it a fundamental dish! Attempt rooster like Parmesan crusted rooster, grilled rooster, or blackened rooster, salmon like baked salmon, pan seared salmon, or grilled salmon, or tofu like baked tofu, crispy tofu, or grilled tofu.

Leftover and make forward ideas: Salads are notoriously suboptimal as leftovers, as they get soggy over time. We wish to plate particular person salads when serving and easily drizzle the dressing over every plate or bowl. If making upfront, chop the elements and retailer them refrigerated in separate particular person containers. Straight earlier than serving, enable the dressing to return to room temperature, then plate every salad. 

Different salad dressing choices embrace Poppy Seed Dressing, Strawberry French dressing, or Citrus Salad Dressing.

Roadmap Designed to Help EHR Integration for Biomarker Testing

By
Robert Day
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0
Roadmap Designed to Help EHR Integration for Biomarker Testing


The Affiliation of Most cancers Care Facilities (ACCC) has made accessible a brand new useful resource to help multidisciplinary most cancers care groups put together, implement, and consider digital well being document integrations for biomarker testing.

Biomarker testing has revolutionized most cancers remedy, offering details about a affected person’s distinctive most cancers, and permitting care groups to personalize remedy to raised tackle the affected person’s particular make-up. Oncology groups think about biomarker testing invaluable for saving extra lives. Nevertheless, integrating biomarker testing outcomes into the EHR may be burdensome. A survey performed in late 2023 by the American Society of Medical Oncology (ASCO) indicated that the “use of the digital well being document” was one of many prime two work stressors for oncologists in energetic observe – and the No. 1 ranked stressor indicated for these working at a non-academic establishment or observe.

“Integration of structured, discrete, searchable information factors can result in standardization of testing and simple retrieval of significant outcomes all whereas lowering the person supplier’s effort on a day-to-day foundation. EHR integration and information administration of biomarkers is nothing wanting transformative,” stated Jennifer Johnson, M.D., Ph.D., in a press release. An ACCC member, Johnson is co-director of the Sidney Kimmel Most cancers Heart Precision Medication Initiative, and affiliate professor on the Division of Medical Oncology and Division of Otolaryngology at Thomas Jefferson College Well being System.

The EHR Roadmap is an interactive instrument designed to assist oncology professionals study important data to determine the muse for EHR integration and descriptions methods for staff preparation, guiding efficient implementation and analysis processes. The EHR Roadmap features a useful resource library with instruments, checklists, publications, and insights from a number of most cancers facilities, giving most cancers groups the assets to simplify EHR integrations into their practices, particularly for biomarker ordering and reporting.

Its instruments have been developed based mostly on outcomes from the ACCC Working Summit: Options for EHR Integration, facilitated by ACCC within the fall of 2023. At that assembly, multidisciplinary oncology professionals gathered to debate challenges to EHR integration and laid the groundwork for the EHR Roadmap.

Karen Huelsman, M.S., L.G.C., an ACCC member and precision oncology lead and genetic counselor at TriHealth Most cancers and Blood Institute, who offered a case examine on the Summit, noticed how wide-ranging most cancers facilities have been in implementation.

“In the course of the Summit, we observed that there have been many facilities on various components of the method, some have been very early on feeling annoyed with EHR integration, and a few completely different facilities have been halfway, the place they’d began implementation, however had run into some obstacles that have been stalling the method,” she stated. “Different facilities had already absolutely carried out their EHR and have been already utilizing energetic and dwell ordering and ensuing methods. On the very forefront have been facilities that have been already constructing reviews that use discrete variants and exhibiting the uptake of utilization by their ordering suppliers.”

The roadmap was created in partnership with LUNGevity and with help from AstraZeneca and Genentech.

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