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Thyroid Hormone Drives Curiosity and Exploratory Conduct, Examine Finds


Methods to Use Progesterone

Earlier than you think about using progesterone, it is very important perceive that it’s not a magic bullet, and that you just get probably the most profit by implementing a Bioenergetic food plan strategy that means that you can successfully burn glucose as your main gasoline with out backing up electrons in your mitochondria that reduces your vitality manufacturing. My new ebook, ā€œYour Information to Mobile Well being: Unlocking the Science of Longevity and Pleasureā€ comes out very quickly and covers this course of in nice element.

After you have dialed in your food plan, an efficient technique that may assist counteract estrogen extra is to take transmucosal progesterone (i.e., utilized to your gums, not oral or transdermal), which is a pure estrogen antagonist. Progesterone is one in every of solely 4 hormones I imagine many adults can profit from. (The opposite three are thyroid hormone T3, DHEA and pregnenolone.)

I don’t suggest transdermal progesterone, as your pores and skin expresses excessive ranges of 5-alpha reductase enzyme, which causes a good portion of the progesterone you take to be irreversibly transformed primarily into allopregnanolone and can’t be transformed again into progesterone.

Best Method to Administer Progesterone

Please notice that when progesterone is used transmucosally in your gums as I counsel, the FDA believes that in some way converts it right into a drug and prohibits any firm from advising that on its label. This is the reason firms like Well being Natura promotes their progesterone merchandise as “topical.”

Nonetheless, please perceive that it’s completely authorized for any doctor to suggest an off-label indication for a drug to their affected person. On this case, progesterone is a pure hormone and never a drug and may be very protected even in excessive doses. That is in contrast to artificial progesterone known as progestins which can be utilized by drug firms, however steadily, and incorrectly, referred.

Dr. Ray Peat has executed the seminal work in progesterone and doubtless was the world’s best knowledgeable on progesterone. He wrote his Ph.D. on estrogen in 1982 and spent most of his skilled profession documenting the necessity to counteract the risks of extra estrogen with low LA diets and transmucosal progesterone supplementation.

He decided that the majority solvents don’t dissolve progesterone nicely and found that vitamin E is one of the best solvent to optimally present progesterone in your tissue. Vitamin E additionally protects you towards injury from LA. You simply must be very cautious about which vitamin E you utilize as most supplemental vitamin E in the marketplace is worse than nugatory and can trigger you hurt not profit.


It’s crucial to keep away from utilizing any artificial vitamin E (alpha tocopherol acetate ā€” the acetate signifies that it is artificial). Pure vitamin E will likely be labeled “d alpha tocopherol.” That is the pure D isomer, which is what your physique can use.

There are additionally different vitamin E isomers, and also you need the whole spectrum of tocopherols and tocotrienols, particularly the beta, gamma, and delta sorts, within the efficient D isomer. For instance of an excellent vitamin E, you may have a look at the label on our vitamin E in our retailer. You should utilize any model that has an identical label.

You should buy pharmaceutical grade bioidentical progesterone as Progesterone Powder, Bioidentical Micronized Powder, 10 grams for about $40 on many on-line shops like Amazon. That’s practically a yr’s provide, relying on the dose you select.

Nonetheless, you have to to buy some small stainless-steel measuring spoons as you have to a 1/64 tsp, which is 25 mg and a 1/32 tsp, which is 50 mg. A standard dose is often 25-50 mg and is taken half-hour earlier than mattress, because it has an anti-cortisol perform and can improve GABA ranges for a very good night time’s sleep.

Sadly, this vendor steadily runs out of product, and if thatā€™s the case, then you should utilize Merely Progesterone by Well being Natura. Itā€™s premixed with vitamin E and MCT oil. Once more, whereas Well being Natura states that its product is for ā€œtopical use solely,ā€ I like to recommend making use of it transmucosally, by rubbing it in your gums.

If you’re a menstruating lady, you need to take the progesterone through the luteal section or the final half of your cycle, which might be decided by beginning 10 days after the primary day of your interval and stopping the progesterone when your interval begins.

If you’re a male or non-menstruating lady, you may take the progesterone day by day for 4 to 6 months after which cycle off for one week. The very best time of day to take progesterone is half-hour earlier than mattress because it has an anti-cortisol perform and can improve GABA ranges for a very good night time’s sleep.

That is what I’ve been personally doing for over a yr with superb outcomes. I’m a doctor so do not need any issues doing this. In case you aren’t a doctor, you need to seek the advice of one earlier than utilizing this remedy, as transmucosal progesterone remedy requires a health care provider’s prescription.

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